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The Hidden Chemicals In Splenda"

By Dr. Janet Starr Hull, PhD., CN

People may think Johnson & Johnson's Splenda", made from sucralose, has

"come to the rescue" as the newest chemical sugar replacement "made from

real sugar." People don't want to hear that it may be just as dangerous as

aspartame, and this "white knight" of sweeteners is no improvement.

Splenda (sucralose) is created in the lab, using a complex process

involving dozens of chemicals you and I can barely pronounce - let alone

consume. To illustrate the alarming "chemical soup" required to create

sucralose, I have listed here the actual process for producing this

sweetener. I highlighted the chemicals in bold type for emphasis.

According to the Splenda International Patent A23L001-236 and PEP Review

#90-1-4 (July 1991), sucralose is synthesized by this five-step process:

1. sucrose is tritylated with trityl chloride in the presence of

dimethylformamide and 4-methylmorpholine and the tritylated sucrose is then

acetylated with acetic anhydride,

2. the resulting TRISPA (6,1',6'-tri-O-trityl-penta-O-acetylsucrose) is

chlorinated with hydrogen chloride in the presence of toluene,

3. the resulting 4-PAS (sucrose 2,3,4,3',4'-pentaacetate) is heated in

the presence of methyl isobutyl ketone and acetic acid,

4. the resulting 6-PAS (sucrose 2,3,6,3',4'-pentaacetate) is chlorinated

with thionyl chloride in the presence of toluene and benzyltriethylammonium

chloride, and

5. the resulting TOSPA (sucralose pentaacetate) is treated with methanol

(wood alcohol, a poison) in the presence of sodium methoxide to produce


The Splenda marketers stress that sucralose is "made from sugar but is

derived from this sugar through a process that selectively substitutes three

atoms of chlorine for three hydrogen-oxygen groups on the sucrose molecule."

While this is true, it is a deceptively simple description, implying that

sucralose is just a benign sugar with a touch of chlorine, and thereby, safe

for consumption.

So sucralose becomes a "low-calorie" sugar with a complicated process

that results in Splenda's chemical formula: 1,6-dichloro-1,


The FDA states in their Final Report on Splenda that sucralose is

"produced at an approximate purity of ninety-eight percent." The other two

percent does not have to be reported to the FDA, nor listed as added

ingredients. So what's in the other two percent? The chemicals used to

synthesize sucralose in the five-step process:

1. Acetone

2. Acetic acid

3. Acetyl alcohol

4. Acetic anhydride

5. Ammonium chloride

6. Benzene

7. Chlorinated sulfates

8. Ethyl alcohol

9. Isobutyl ketones

10. Formaldehyde

11. Hydrogen chloride

12. Lithium chloride

13. Methanol

14. Sodium methoxide

15. Sulfuryl chloride

16. Trityl chloride

17. Toluene

18. Thionyl chloride

Now you can see why I do not recommend sucralose for pregnancy or for

children, especially after reading this list.

It's time to admit that there is no free ticket to eating all the

sugar-free products you desire without paying the high price of harming your

body in the long run. Laboratory chemicals are not the answer.

From Dr. Janet Starr Hull's website Splenda Exposed:

This information is based on research from Dr. Janet Starr Hull. For more

information on Splenda, see Dr. Hull's newly released book Splenda": Is It

Safe Or Not? at

About The Author
Dr. Janet Starr Hull publishes a monthly health newsletter covering a

wide range of important health topics. To sign up for her free newsletter or

to view past articles, visit

An artificial sweetener expert, Dr. Hull is the author of "Sweet Poison"

an expose on the dangers of aspartame, and "Splenda": Is It Safe Or Not?",

her newest book on the dangers of sucralose found in Splenda. Dr. Hull also

features her detoxification program and Detox Kit, proven highly effective

in cleansing the body of food chemicals and environmental toxins.


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