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Ozone Therapy: Exploring the Benefits and Potential Side Effects

Ozone therapy is a medical procedure that introduces ozone gas into the body. This remedy has grown in popularity in recent years due to its potential health benefits. However, it is also a controversial topic because of the perceived risks. In this article, we look at what ozone therapy is, its benefits and possible side effects.

What is Ozone Therapy?

Ozone therapy is a method that has a wide range of therapeutic effects. In therapeutic concentrations, ozone has an immunomodulatory, anti-inflammatory, antibacterial, antiviral, antifungal, and analgesic effect.

The main purpose of this method is to improve blood flow to small blood vessels (capillaries) and oxygenate the cells. Ozone reacts with fatty acids found in red blood cell membranes. Peroxides are formed - quickly reacting chemical compounds necessary for the connection of oxygen in the blood. Ozone therapy is easy to use, highly effective, and well tolerated - even pregnant women can resort to its help.

Indications for ozone therapy

Indications for ozone therapy refer to the specific health conditions or symptoms that may potentially benefit from ozone therapy. This therapy can be used to treat a variety of conditions, including:

  • Treatment of chronic diseases of the cardiovascular system: arterial hypertension, coronary heart disease.
  • Diseases of the urinary system.
  • Infectious and inflammatory diseases of the skin and mucous membranes: fungal and pustular infections, atopic dermatitis, acne, acne, etc.
  • Rehabilitation after injuries or major operations.
  • Diseases of the musculoskeletal system.
  • Cosmetic problems: elimination of cellulite, local fat deposits, scars and scars, fight against age-related skin problems.
  • Diseases of the reproductive system: prostatitis, infertility, inflammatory processes.
  • Chronic headaches, migraines, cerebrovascular accidents.
  • Autoimmune disorders: helps treat autoimmune disorders by reducing inflammation and stimulating the immune system.
  • Dental problems: this kind of therapy is sometimes used in dentistry to treat infections and relieve pain.

Although ozone therapy is not a common medical treatment, it has gained popularity among some alternative medicine practitioners. However, be sure to consult with a licensed healthcare provider before considering ozone therapy as a treatment option.

Benefits of Ozone Therapy

Proponents of ozone therapy claim it offers many health benefits, including:

Increase oxygen supply

Ozone therapy is thought to increase the delivery of oxygen to body tissues, thereby improving cellular function and metabolism.

Stimulate the immune system

Ozone therapy is thought to stimulate the immune system, helping the body fight infection and disease. 

Relieve the pain

Ozone therapy is thought to relieve pain by reducing inflammation and increasing blood flow to the affected area. The analgesic effect of ozone therapy is due to two aspects. Firstly, it is an anti-inflammatory effect, which leads to the elimination of pain associated with inflammatory diseases, and secondly, ozone destroys algopeptides - pain molecules that transmit signals from pain receptors to the central nervous system. This property is used to treat severe chronic pain syndrome.

Anti-aging effects

Ozone therapy is believed to have anti-aging effects by improving the delivery of oxygen to the body's tissues and reducing oxidative stress.

Scientific research supports some of these claims. For example, a study published in the International Journal of Ozone Therapy found that this kind of therapy improved blood circulation and reduced inflammation in patients with chronic obstructive pulmonary disease (COPD). Another study, published in the Journal of Alternative and Complementary Medicine, found that ozone therapy reduced pain and improved mobility in people with knee osteoarthritis.

Possible side effects of ozone therapy

Despite the potential benefits of ozone therapy, it also has potential side effects. Possible side effects include:


Ozone can cause inflammation when it comes in contact with body tissues.

Respiratory problems

Ozone can irritate the respiratory system and cause coughing, wheezing and shortness of breath.

Oxidative stress

Ozone increases oxidative stress in the body, which damages cells and tissues.


Ozone therapy can increase the risk of infection if proper hygiene is not followed during administration.

It is important to note that the risk of side effects may depend on the method and dosage of ozone therapy used. For example, inhalation therapy may cause breathing problems more than other methods.

Safety Concerns Surrounding Ozone Therapy

Because of the potential risks associated with ozone therapy, its use poses safety concerns. Ozone therapy is not approved for medical use in some countries, while others have regulations restricting its use.

In the United States, the Food and Drug Administration (FDA) does not approve ozone generators for medical use. However, ozone therapy is legal in some states for use by licensed healthcare providers. The American Cancer Society also does not endorse the use of ozone therapy as a cancer treatment because there is insufficient evidence to support its effectiveness.


Ozone therapy is a controversial medical procedure that involves injecting ozone gas into the body. Proponents claim it offers numerous health benefits, including increased oxygenation, immune system stimulation, pain relief and anti-aging effects. However, it also has potential side effects, including inflammation, respiratory problems, oxidative stress, bleeding disorders, and infections.

It is important to consult with a licensed healthcare provider before considering ozone therapy as a treatment option. They can provide guidance on whether the therapy is appropriate for specific health conditions and help determine the potential risks and benefits. As with any medical treatment, safety should be the top priority. 

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